Which one of the following statements regarding the complement cascade is incorrect?
Which of the following is NOT common to the lectin and alternative pathway of complement activation
Pattern recognition receptors (PRR) are important recognition molecules of the innate immune system. Which one of the following statements best describes their function?
Which one of the following statements is correct?
Which one of the statements about B cell interaction with their antigen is incorrect?
Which one of the following is correct regarding the structure of MHC molecules?
Which one or more of the following statements about T cell function is correct?
A: T cells which express CD4 can interact with HLA A, B and C antigens.
B: Helper T cells interact with MHC Class II - peptide complexes displayed by antigen activated B cells in secondary lymphoid tissues, resulting in isotype switching
C: T cells which express CD4 can bind free antigens in infected tissues, and help phagocytes to remove them.
D: Cytotoxic T cells recognise viral peptides held in Class I MHC molecules on infected tissue cells.
Which one or more of the following statements is correct regarding T cell receptors?
A: T cell activation can only proceed in vivo when the V and J domains of the alpha chain and V, D and J domains of the beta chain of a T cell receptor interacts with peptides held in the cleft of an MHC molecule.
B: Most thymic T cells die, either because they fail to bind self MHC-peptide complexes displayed on cells in the thymus, or because they bind the complexes with too high an affinity.
C: Somatic mutation and somatic gene rearrangements resulting in combinatorial and junctional diversity contribute to the generation of diversity of both B and T cell receptors.
D: T cells which exit the thymus express either CD4 or CD8 co-receptors, and bind self MHC-peptide complexes with low affinity.
Which one of the following statements about T cell activation is correct?
Which one of the following statements regarding immunodeficiencies is incorrect?