Quisitor - Take Quiz

1

Which of the following is NOT a generally recognised cause of memory impairment?

Surgical resection

Temporal lobe epilepsy

Bilateral thalamic infarction

Chronic alcoholism

Statins

2

Which of the following statements about memory systems is INCORRECT?

The declarative and procedural systems can become impaired independently

Skill acquisition is part of procedural memory

Working memory is important in executive function

Episodic memory is heavily dependent on temporal, spatial and emotional context

Damage to the prefrontal cortex will most likely affect procedural memory

3

Which of the following statements about lesion-associated memory impairment is CORRECT?

Retrograde amnesia refers to the inability to recall events that happened after an amnesia-inducing injury

Episodic memory impairment is often associated with lesions to neocortical areas of the brain

Amnesia is often observed following unilateral hippocampal resection

Patient HM's anterograde amnesia was responsible for his inability to recognise people he had recently met

The enterorhinal cortex is not associated with amnesia-inducing lesions

4

Mild cognitive impairment (MCI) does not typically result in:

Complaints of problems with object-place associations

Reduced ability to cope with everyday activities

Objective memory impairment

A subsequent transition to dementia

5

Alzheimer's disease (AD) is the commonest cause of dementia. Which ONE of the following statements regarding AD is INCORRECT?

It is graded in stages

It involves significant observable changes in the hippocampus compared with normal controls

Both encoding and retrieval of memories appears to be affected

Glucose uptake is impaired, especially in the temporo-occipital association cortex

Launguage impairment in AD is most often 'Wernicke'-type, i.e. fluent.

6

The pathophysiology of AD includes the formation of 'neurofibrillary tangles'. Which one of the following is this NOT associated with?

Genetic predisposition, the profile of which appears to vary between the senile and non-senile onset forms of AD

Plaque formation between cells

Overproduction of β-amyloid protein

Apolipoprotein E1

Collapsed microtubules and cell death

Take Quiz

HP4 Lecture 8

1

2

3

4

5

6