JCU MB4 Term 2 Week 2 (Leukaemia)

1

78yo, anaemia and fatigue for 2 years. Splenomegaly. Peripheral blood smear shown. What is the likely diagnosis?

Blood Film - CLL


2

58yo, anaemia, splenomegaly. Peripheral blood smear shown. What is the likely diagnosis?

Blood Film - CML


3

38yo, 3 days of fever with a sore throat. Peripheral blood smear shown. What is the likely cause?

Blood Film - Allergy


4

10yo boy, right groun pain and two enlarged lymph nodes for 7 days. He has an infected toenail. Lymph node biopsy shown. What is the likely diagnosis?

Lymph node - Infection


5

48yo, fever, splenomegaly, enlarged lymph nodes. Lymph node biopsy shown. What is the likely diagnosis?

Lymph node biopsy - Hodgkins Lymphoma


6

38yo, four week fever, hepatosplenomegaly. Peripheral blood smear shown. What is the likely cause?

Blood Film - ALL


7

58yo male, cervical lymphadenopathy 6 months. Fever, weight loss. Biopsy of 2cm of lymph node tissue reports multiple well-formed granulomas with central caseous necrosis. What is the most likely diagnosis?


8

38yo, 3 days of fever, sore throat. Peripheral blood smear shown. What is the likely cause?

Blood Film - Bacterial Infection


9

6yo girl, 1 month of fatigue, headache, vomiting and fever. Hb 80g/L, Platelets 56k, WCC 32,550. Flow cytometry reported 70% CD10 & CD10 +ve. Peripheral blood smear shown. What is the likely diagnosis?

Blood Film - ALL


10

38yo, high fever. Peripheral blood smear shown. What is the likely cause?

Blood Film - Reactive Lymphocytes


11

A 28yo man, mediastinal lymphadenopathy. Reports recurrent fever, night sweats, mild weight loss for 6 months. Enlarged cervical lymphnodes. Image shows lymph node biopsy. What is the most likely diagnosis?

Lymph node - Hodgkin's Lymphoma


12

42yo, fever for 3 weeks, hepatomegaly. Peripheral blood smear shown. What is the likely diagnosis?

Blood Film - AML


13

65yo male, splenomegaly, bleeding tendency. Hb 13g/dL. Peripheral blood smear shown. What is the likely diagnosis?

Blood Film - Essential Thrombocytosis


14

A 9yo girl develops widespread pinpoint skin haemorrhages. She recovered from a flu-like illness 1 week earlier. Laboratory findings reveal a platelet count of 20,000/uL but no other abnormalities. Her bone marrow shows an increased number of megakaryocytes. The platelet count is normal after 2 months. What is the most likely diagnosis?


15

2yo male, fever for 3 weeks with enlarged lymph nodes (++). Peripheral blood smear shown. What is the likely diagnosis?

Blood Film - ALL


16

61yo female presents with cough, fever, SOB, rigors and tachycardia for 3 days. Peripheral blood smear shown. What is the likely diagnosis?

Blood Film - Neutrophila


17

78yo fever, splenomegaly, lymphadenopathy. Peripheral blood smear shown. What is the likely diagnosis?

Blood Film - CLL


18

A 72yo retired man. Sever back pain, confusion, pale. Has had polyuria and polydipsia for 3 week, recurrent fever for 3 months. Labs: Hb 9g/dL, WBC 6.8x10^9^/L, ESR 80mm/h, Spine XR shows multiple punched out lytic lesions in ribs and vertebrae. What is the most likely diagnosis?


19

48yo, fever, splenomegaly, lymphadenopathy. Lymph node biopsy shown. What is the likely diagnosis?

Lymph node - Hodgkins


20

57yo male, fever, splenomegaly, lymphadenopathy for 6 months. Lymph node biopsy shown. What is the likely diagnosis?

Lymph Node - Non-Hodgkins


21

42yo female, pale, splenomegaly. Peripheral blood smear shown. What is the likely diagnosis?

Blood Film - Haemolysis


22

57yo male, fever, splenomegaly, lymphadenopathy for 6 months. Lymph node biopsy shown. What is the likely diagnosis?

Lymph node - NS HL


23

A 2yo boy, high fever and weakness for 12 days. Skin purpura and bleeding lips. Mild splenomegaly. No lymph node enlargement. Most likely diagnsosis?


24

22yo male, fever, sore throat for 6 days. Generalised lymphadenopathy. Mild macrocytosis. Monospot test positive. Peripheral blood smear shown. What is the likely diagnosis?

Blood Film - Agglutination


25

60yo male, weight loss, fatigue, upper abdominal discomfort. Splenomegaly. Hb 9g/L, MCV 102fL, WCC 40,000/uL. Blood film shows mature and immature granulocytes, myelocytes, basophils and occasional myeloblasts. What is the most likely diagnosis?