DMF Week 8 SAQ

1

Which one of the following statements is correct?


2

Which one or more of the following statements about HIV transmission is correct?

A - Macrophages and helper T cells can be infected by HIV because both cell types express CD4.

B - In vitro infection of macrophages and T cell lines by different sub-types of HIV is determined by the expression of specific chemokine receptors on these cells.

C - Newly released HIV virions require the action of a virus encoded protease to become fully infectious

D - HIV is a DNA virus which integrates into the host cell genome and thus evades the immune system.


3

Which one or more of the following statements about pandemic influenza is correct?

A - The existing influenza vaccine can provide protection against pandemic influenza

B - Aquatic water birds have undergone mass slaughter in Asia in an attempt to curb the spread of avian influenza to humans

C - A new pandemic of influenza virus is predicted to spread around the globe in about 12 months, which will be sufficient time for a vaccine to be made against the newly emerging strain

D - Antivirals such as the neuraminidase blockers may be effective against a newly emerging strain of virus but the supply might be insufficient.


4

Which one or more of the following statements about cervical carcinoma is correct?

A - HPV types 16 and 18 have been associated with cervical carcinoma

B - There is currently no therapeutic vaccine nor adequate treatment for cervical carcinoma

C - A virus-like particle (VLP) vaccine recently licensed may be ably to prevent new infections with HPV and therefore lower the incidence of cervical carcinoma

D - In cervical carcinoma cells the HPV genome can be found integrated into the chromosome


5

A 37 year old HIV positive male patient is admitted to hospital because of weight loss and an increasingly frequent non-productive cough and breathlessness. Chest X-ray reveals an interstitial pneumonia. Which one or more of the following microorganisms are likely causes of his lung problems?

A - Klebsiella pneumoniae

B - Pneumocystis jiroveci (carinii )

C - Streptococcus pneumoniae

D - Mycobacterium avium-intracellulare (MAC)


6

Which one of the following statements are correct regarding the characteristics of Chlamydia trachomatis?