DMF MSE 1 2011

1

Which one of the following statements about bacterial capsules is correct?


2

Which one of the following statements about exotoxins is correct?


3

Choose the correct statement regarding urinary tract infection:


4

Which of the following statements about bacterial virulence determinants is not correct?


5

Miss LC, a 24 yr old student, presented to her GP with a 2 day history urinary frequency and dysuria. She had been previously well, having just returned from an interstate visit with her boyfriend. A mid-stream specimen of urine was collected and sent promptly to the laboratory for microscopy and culture. Which one of the following sets of results from laboratory testing of the urine sample would confirm the diagnosis of acute cystitis?


6

Which one of the following statements regarding Clostridium botulinim and/or botulism is incorrect?


7

Which one of the following is not known to be a resistance strategy of Gram negative rods to aminoglycoside antibiotics, such as streptomycin?


8

The general antimicrobial action of metronidazole is best described as:


9

Which one of the following is not a mechanism of intrinsic resistance to antimicrobials?


10

Which one of the following strategies cannot be used to identify a specific antigen?


11

Which one of the following is not characteristic of Pseudomonas aeruginosa growing in a biofilm?


12

The medical officer in a regional town was notified of a cluster of cases of gastroenteritis (with symptoms of profuse vomiting and some diarrhoea) among children attending a local pre-shcool. Laboratory investigations indicated that Staphylococcus aureus was the cause. Which one of the following activities undertaken by all the affected children would best explain how they may have been infected?

Notes on questions 13-15:
These were not included in the recording, but here are some useful points:

  • Q13 covered bacterial toxins. A main learning point was that LT has the same mechanism as cholera toxin.
  • Q14 covered a case with a heart murmur/endocarditis. Main learning points were that it was important to get culture results before AB therapy, high and prolonged doses are required, and that intermittent shedding of organisms from the heart valve puts the patient at risk of abscesses in distant organs.
  • Q15 covered sterilisation procedures. Main learning points included the information required to determine sterilisation time (amount of pre-existing organism etc), the D value and fact that even steam sterilisation cannot and will not kill everything.